Is clove oil effective for toothache? Clove oil and oral health How to use Is it effective? Side effects Other treatments When to see a dentist Prevention We include products we think are useful for our readers. Clove oil and oral health. Share on Pinterest Clove oil has long been used as a home remedy for toothache. How to use clove oil to treat toothache. Is it effective? Share on Pinterest Clove oil may ease toothache when applied to the gums. Side effects. Other toothache treatments. When to see a dentist.
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Measure content performance. Develop and improve products. List of Partners vendors. Toothaches can be distressing, particularly if you can't get to the dentist's office immediately. While some people will reach for an over-the-counter topical anesthetic like Orajel or Anbesol, others will head to the health food store for a bottle of clove oil —a natural remedy used for centuries to treat tooth pain. While it is safe when used correctly and may provide you with relief, there are limitations to its use and things you should know before using it or any therapeutic oil.
Popular in Ayurvedic medicine and traditional Chinese medicine , cloves were once inserted whole into an infected cavity or applied as a topical extract to relieve pain and inflammation. By the early 19th century, the active ingredient, Eugenium aromaticum, was combined with magnesium oxide to create a temporary filling material.
The magnesium oxide has since been replaced by zinc oxide to produce zinc oxide eugenol ZOE , a temporary filling cement still popularly used in dentistry and endodontics. Cloves are dried flower buds taken from a tree of the Myrtaceae family. The oil is usually extracted through steam distillation; other producers rely on chemical solvents and boiling to obtain the prized oil.
Eugenol is the chemical that gives clove its spicy scent and pungent flavor. When applied to tissues, it creates a warming sensation that Chinese herbalists believe treat yang deficiencies. Clove oil works similarly to capsicum in peppers by stimulating the production of a protein known as trans receptor potential vanilloid-1 TRPV-1 which, in turn, desensitizes nerve endings near the surface of the skin. It also exerts potent antibacterial properties that can aid in healing and prevent infection.
Clove oil, which can be colorless or have a slightly yellowish tinge, is often used in dentistry to treat pain from a dry socket following the extraction of a tooth. While there had been some suggestions that clove oil is just as effective as benzocaine in treating toothache, the U. Food and Drug Administration FDA downgraded eugenol, citing that the evidence supporting its use was lacking.
Clove oil should never be applied to the gums undiluted as it can cause irritation and may lead to toxicity. To do this, apply a small amount of diluted clove oil to the inside of your elbow. Be sure to know the signs and symptoms of anaphylaxis , a potentially life-threatening allergic reaction:. You can shop for clove oil online or in natural food or health stores. To find the best quality clove oil, follow the tips below:. Traditionally, clove oil has been used for easing digestive upset, relieving pain, and helping with respiratory conditions.
Research has found that clove oil may have benefits for dental and topical applications, for treating infections, and even fighting cancer. As with any essential oil, make sure to use clove oil safely. Always talk to your doctor if you have any questions or concerns before using clove oil. Essential oils are claimed to offer many health benefits. This article explains everything you need to know about essential oils and their health….
Cloves are a flavorful spice in baked goods and Indian cuisine, but they also have benefits for your health. Here are 8 health benefits of cloves.
How can you safely use clove oil as a natural treatment for toothaches? Learn three different ways to use this treatment. Research has shown that chamomile oil can benefit your health in numerous ways. Learn how it can help with digestion, anxiety, depression, pain relief,. Health enthusiasts have long raved about the countless benefits of wheatgrass, and for good reason.
We have 11 reasons why you should add it to your…. Deer antler velvet supplements, or simply deer antler supplements, are touted to offer health benefits. This scavenging effect of eugenol is due to presence of allyl group in its structure. Another study by Gulcin et al. Clove oil polyphenol eugenol illustrates potent antibacterial potential against numerous strains of Gram-positive Enterococcus faecalis , Staphylococcus epidermidis , Streptococcus pyogenes , Staphylococcus aureus , Streptococcus pneumonia , Listeria monocytogenes , Bacillus cereus , Bacillus subtilis and Gram-negative E.
Eugenol damages cell membrane and cell wall, inducing cell-lysis in Gram negative and Gram positive bacteria resulting in leakage of intracellular fluid along with lipid and protein contents. At concentration of 0. Eugenol has potentiality to constrain viral infection and replication categorically against herpes simplex viruses i.
Eugenol has been validated to be adequate against herpes simplex virus-1 HSV-1 clinical isolates. The principal methoxyphenol of clove oil; eugenol has documented anti-inflammatory potential. Eugenol suppresses cyclooxygenase COX -2 expression and tumor necrosis factor TNF signaling, whereas eugenol oligomers avert inflammatory cytokine expression in macrophages and NF-kappaB nuclear factor-kappaB activation.
According to findings of Koh et al. Examination of lung tissues and bronchoalveolar lavage fluid BALF suggested anti-inflammatory effect due to reduced production of pro-inflammatory cytokines. Cyclooxygenase activity is prompted by LPS, cytokines and growth factors. It also protected against chemically induced dysfunction of macrophages and balanced the pro-inflammatory mediators. Further clinical studies are required to authenticate the use of eugenol and its other active derivatives as anti-inflammatory agents on dendritic cells, along with their modulating effects on cytokines and autoimmune inflammatory diseases.
Eventually, results from these clinical trials would significantly improve the immune-protective application of eugenol. Recent clinical studies of medicinal plants used in numerous traditional medicines have triggered the invention of various chemotherapeutic drugs, like camptothecin, vinblastine, taxol and vincristine. Breast cancer is the most prevalent type of malignant cancer among women and is ranked fourth common reason of cancer related deaths in the world.
Eugenol repressed growth of human breast cancer cells by initiation of cell death both in time and dose dependent manner. Essential oils being extracted by hydro distillation of roots and barks of Uvariodendron angustifolium containing Inducible cyclooxygenase COX-2 inhibitors have been considered as cancer chemo-preventive and anti-inflammatory agents.
According to findings of Kim et al. Remedies for colon cancer through administration of eugenol resulted in decreased concentration intracellular non-protein thiols. Additionally, DNA fragmentation caused by amplification of reactive oxygen species ROS is considered as a core reason for apoptosis in eugenol-subjected colon cancer cells.
Eugenol not only transmitted apoptotic signal through reduction of non-protein thiols resulting in decreased potential of mitochondrial membranes, eventually leading to increased production of ROS.
Novel strategies in cancer prevention have initiated the use of eugenol as a potential chemotherapeutic agent. Synergistic effect of eugenol with chemo-preventive drugs has been reported to reduce the drug toxicity on normal cells and augment the cytotoxicity of administrated synthetic agents.
Among all investigated phenyl-propanoids, eugenol explicated maximum cytotoxicity and reduced hemolytic activity validating its use as a chemo-protective agent without any adversative toxicity. Currently, chemo-protective agents being practiced to cure malignant melanoma; typically the most antagonistic skin cancer occurring in melanocytes are unsatisfactory.
They suggested inhibitory mode of action of eugenol as it causes cell cycle arrest and induces apoptosis. In an experimental trial Koh et al. Cytotoxic concentrations of eugenol resulted in reduction of ATP utilization of oxidative stress and an increase in the polyamines and glycolytic metabolites, in normal oral cells and oral squamous cell carcinoma.
Another group of researchers have highlighted the inhibitory potential of eugenol against expression of matrix metalloproteinase MMP-9 activity in PMA-stimulated HT cells via inactivation of ERK proteins. Consequently, they evaluated that eugenol from cloves, explicitly revealed highest inhibitory effect on hydrogen peroxide H 2 O 2 than other ROS reactive oxygen species , and was able to halt lipid peroxidation and DNA oxidation, induced by hydroxyl radical.
Therefore, eugenol could be accessible as an outstanding agent for prevention of metastasis associated to oxidative stress.
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